The Institute of Genetic Epidemiology, Medical Center – University of Freiburg is looking for a

Research Assistant for discovering Protein–Trait Associations Through Causal Inference (m/f/d)

The Statistical Genomics Group (Emmy Noether Group Leader: Dr. Pascal Schlosser) at the Institute of Genetic Epidemiology generates new insights into the (patho-)physiology of complex human traits and diseases, which arise from the combination of genetic predisposition and environmental influences. The proposed project is focused on the development and application of phenome-wide Molecular Causal inference Network analysis by integrating pre-computed molecular prediction models (e.g., cis-heritable plasma proteins, gene expression) with genome-wide association data from complex traits. This effort combines data from large biobanks and consortia (e.g., UK Biobank, FinnGen, All of Us, MVP), accounting for ancestry-specific differences and using multiple protein prediction models.

We offer:

an exciting job within our highly motivated multidisciplinary team of statisticians, bioinformaticians, and clinician scientists
personalized supervision at the forefront of integrative biomedical sciences
an international environment
Flexible working hours and compensation in accordance with student/research assistant pay scale.
employee offers / health offers (e.g. Hansefit)

Your mission:

process and harmonize GWAS summary statistics from large biobanks
perform GWAS across diverse health traits and ancestries
compare results across different models
contribute to the development and documentation of an open-source R package that integrates molecular models with GWAS data to enable systematic network-based causal inference
result dissemination, visualization and reporting

Your qualifications:

a background in computational biology or a related field
a Bachelor’s or Master’s degree in bioinformatics / computational biology / mathematics / physics / epidemiology / data sciences or a comparable subject
experience in programming (R, Python, ...)
proficient knowledge in written and spoken English
independent, target-oriented working manner
strong commitment to research ethics and teamwork
good communication skills

The position is initially limited to one year, with a monthly workload ranging from 25 hours/month up to the maximum number of hours permitted for a low-income employment (to be agreed upon).

We look forward to receiving your application, including your possible starting date, by August 10, 2025.

University Medical Center Freiburg
Institute of Genetic Epidemiology
Dr. Pascal Schlosser - Group Leader Statistical Genomics
Hugstetter Str. 49, 79106 Freiburg

For further information please contact Dr. Pascal Schlosser:

pascal.schlosser@uniklinik-freiburg.de

General information: Salary is assigned according to a pay scale. Unless prevented by operational or legal reasons, full-time positions are generally open to those wishing to job share. Where two candidates are equally suitable for a post, severely disabled candidates are given priority. Employment decisions are made by the Personnel Department.

Research Assistant for discovering Protein–Trait Associations Through Causal Inference (m/f/d)

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